A system is "created" in my opinion, whereas a system of systems is "evolved." Typically, when developing a system, we begin with a blank slate and a set of predetermined specifications. The end product is a "designed" item that is completed once it satisfies those requirements. A System of Systems, however, is rarely complete; as new autonomous systems join or depart the collective, it expands and changes. I don't think this is a mechanical process, but rather a biological one. According to this viewpoint, you can only "guide" a SoS's development rather than "design" it in the conventional sense. We must welcome change and uncertainty in order to adopt this evolutionary mindset. The most successful examples of SoS, such as the global internet, were, in my opinion, never intended to be a single entity. Over many years, thousands of separate networks came together to form them. I firmly think that flexibility and timeliness make a difference. A System of Systems is a living, breathing entity that continuously reconfigures itself to meet new challenges, while a system is a snapshot in time.